Animal develop kidney failure every year and one-third

Animal testing has contributed to many life saving with the discovery of cures and treatment. Humans shares about 95% of genes with a mice, which make them one of the most effective model for experiment on human body.1.How Animal testing benefits us from kidney failureAn average of 5,000 people will develop kidney failure every year and one-third of people with kidney failure would had pass away without a regular dialysis or kidney transplant. Animal experimentsJoseph E. Murray is an American plastic surgeon who had succeeded in performing the first human kidney transplant in 1954.Joseph and a few scientists were involved an experiment to master the surgical technique for organ transplant. In order for them to master those surgical technique, it was first carried out on bigger animal such as pigs and dogs in 1950’s. Even after the surgical technique was perfected, the experiment isn’t successfulWhy is it so?As rejection of new organ became the major problem as many patient who had undergo the kidney transplant does not survive as acute rejection will lead to another organ failure.That’s when Cyclosporine came in and deal with it. It was discovered in 1972, which is extracted from a type of fungus, And was tested on mice and found that it helps to prevent the rejection of a new organ in mice. Thereafter, was tested on dogs that have undergone organ transplant, thus resulting in a 3 times increase in survival rate thanks to Cyclosporine.What’s animal testing has done for humans? Without animal testing, it would be impossible for human-being to perfected the surgical technique and many more would had pass-away due to illness that can only be treated through surgery.With the help of animal testing, around 16,000 kidney patients benefited from kidney transplants each year, without the need to go for regular dialysis anymore.2. How Animals testing benefits us from cancerResearch show that every 1 out of 10 women will diagnosed with breast cancer in their lifetime. Animal experimentsStudies in animal testing has shown that hormone changes can influence the breast tumors cells in rats. Tamoxifen which was rather accidental discovered in 1967 in a process of searching for emergencies contraceptive with animal testing.Later on Tamoxifen was tested in animal testing, it show a positive result of preventing the growth of cancers cellsWhy experiment on animal?Animal testing is a way where human can do research with trial and error in search for cure to specific illness before testing it on humanUsing animals in cancer research, by growing human tumour cells in laboratory cell cultures.Without animal testing it is impossible to show that the cell culture results were relevant and reliable to humans and will respond to the same drugs in the patientsWhat’s animal testing has done for humans?With the help of animal testing, scientist was able to find a treatment for breast cancer. Tamoxifen was introduced in the 90s, is a medication that is used to help prevent and treat breast cancer in women or men by stopping the growth of hormone breast cancer cells, which had lead to 30% decrease in death rates from breast cancer. Today, breast cancer is listed as the second most survivable female cancer, with an increase of 77% in survival rate. And has proven that it helps to prevent breast cancer in high-risk patients